Every month at Sycuan, we have a wide variety of casino table games such as casino poker promotions and special. A story luxury hotel tower featuring + guest rooms and a range of onsite amenities. Mega Quads is back at the Sycuan Poker Room! Qualifying hands win prizes Monday - Sunday from Noon - Midnight, or following Grave Super Yahtzee until 8AM! Sycuan Casino Resort is a Native American casino in El Cajon, California and is open daily 24 hours. Poker is open 24 hours a day, 7 days a week. sycuan casino buffet. Poker is back and now open 24/7! Guests are required to follow all health and safety protocols while playing and staying with us. Sycuan offers one of the biggest poker rooms in San Diego featuring 17 poker tables. Join a poker tournament or sit in on a game of Texas Hold'em today. The casino's square foot gaming space features. . Sycuan Casino Resort | followers on LinkedIn.