Experience. Browse our selection of Casino hotels & resorts in San Luis Obispo, CA for the ultimate stay & play vacation. Casinos with slot machines in San Luis Obispo, CA · [HOST] City Casino Online · [HOST] Knights · [HOST] Air Inc · [HOST]l Coast Casino · 5. mi. Make your casino vacation a sure bet with. mi. Non-Stop Gaming Action | Hotel & Spa | Live. Top 10 Best Casinos With Slot Machines Near San Luis Obispo, California ; Paso Robles Casino. ; Kon Tiki Inn. mi. . Is there an onsite casino at Motel 6 San Luis Obispo, CA - South? No, this motel doesn't have a casino, but Central Coast Casino (min drive) is nearby. Our spacious, , square foot casino floor features 2, of the newest, hottest slot machines, plus bar top gaming at the Center Bar. The best way to get from Chumash Casino Resort, Santa Ynez to San Luis Obispo costs only $14 and takes just 1¼ hours. Bingo is open Sunday. Chumash Casino Resort is a one-of-a-kind entertainment destination in Greater Santa Barbara, California. ; Madonna Inn. Cool and friendly casino, bar, and kitchen with live Poker, Blackjack, 3-Card Poker, Ultimate Tex Find Your Escape in the Heart of Wine Country. Find the travel options that best suit. Top 10 Best Casinos in San Luis Obispo County, CA - April - Yelp - Central Coast Casino, Paso Robles Casino, Outlaws Bar & Grill, Sunshine Poker League.